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WHY do people get depressed?

There are an enormous variety of reasons why people get depressed, some which are identified in the following list:

  • Comorbid conditions of personality disorder, anxiety disorders or substance abuse increase the risk of depression.

  • Depression results from a complex interplay between genetic liability and environmental factors.

  • Depression is often linked to life changing events.

  • Childhood adversity (neglect and abuse experiences) is a risk factor for major depression.

  • Stress.

  • Urbanisation is associated with increased stressors and adverse life events.

  • Rurality may be associated with increased isolation and limited facilities.

  • Postnatal depression affects approximately 10% women.

  • Sexuality variations increase the risk of depression because of prejudice and stigma.

  • Social factors may increase the risk of depression:

    • Unemployment.

    • Dissatisfaction with employment, includes the phenomenon of burnout.

    • Poverty and debt.

    • Isolation, loneliness.

    • Bereavement.

    • Relationship problems.

  • Increasing age:

    • People > 65 years are at increased risk of depression.

    • People >85 years are at even greater risk of depression.

    • Increased risk of depression in old age is related to physical disability and the onset of new chronic medical illnesses which cause a reduction in functional ability.

    • Vascular disease causing a vascular depression.

  • Chronic disease increases the risk of developing major depression:

Chronic Disease

Risk of Major Depression

Diabetes 11-15%
Recent Myocardial Infarction 15-23%
Coronary Artery Disease 15-23%
Post-Stroke (at 3-4 months) 9-31%
Parkinson's Disease 50%
Multiple Sclerosis 16-30%
HIV 10%
Rheumatoid Arthritis 20%

 

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WHY is depression important?

  • Depressive disorder is a common, complex and debilitating condition with potentially fatal consequences (Montgomery, 1995; Manning, 2003).

  • Depression affects one in five people at some point in their lives (Depression Alliance, 2006).

  • Depression is frequently inadequately recognised and ineffectively treated and leads to disability equivalent to that of chronic medical conditions (Paykel, 1992). 

  • Depression is predicted to be the highest-ranking cause of disease burden in developed countries by 2020 (WHO, 2001). 

  • Depression places a significant burden on the individual, their family, the NHS and the economy.

  • The total cost of depression in people aged over 15 years in England in 2000 is estimated to be in excess of £9billion (Thomas, 2003).

  • Approximately 10% of patients who consult their GP meet the criteria for mild or moderate depression (DTB, 2003).

  • The National Service Framework (NSF) for Mental Health (DoH, 1999a) stated that 25% of routine GP consultations are for people with a mental health problem; the latest estimate is 30% of consultations are for people with mental health problems (MHF, 2005). 

  • Mild to moderate depression is managed almost entirely within primary care and although the majority of patients’ symptoms resolve within 6-12 months, approximately 20% of patients have symptoms which persist, becoming chronic and disabling. 

  • The World Health Organisation (WHO) has identified chronic relapsing depression as one of the four most disabling illnesses in the world (Murray, 1997). 

 

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WHY do clinicians need to know?

  • Depression is a personal and complex illness experience. 

  • It is important for healthcare professionals to understand the different aspects of the patient experience relating to antidepressant medication; the beginning of medication, adherence to the medication regimen, and stopping treatment when appropriate. 

  • Involving patients with depression in research about depression will help to identify the important questions and is more likely to produce results that can be implemented and disseminated within the wider healthcare arena. 

 

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WHY refer patients to exercise referral schemes?

The benefit of exercise to physical health is well-known, but the benefits to mental health are less well-known.  A study undertaken by The Mental Health Foundation (MHF, 2005) shows that a supervised programme of exercise is as effective as antidepressants in treating mild or moderate depression.  This provides good evidence for promoting exercise as a first-line treatment.  Alongside this, exercise has few negative side effects and has a number of associated benefits:

  • It can be used to treat patients who have both mental and physical health problems.

  • It is associated with reduced anxiety, decreased depression, enhanced mood, improved self-worth and body image, and improved cognitive functioning.

  • It is a sustainable recovery choice.

  • It promotes social inclusion.

  • It is a popular treatment.

  • It is a normalising treatment.

  • It is less expensive than antidepressant medication.

  • It is an effective prophylactic against depression.

 

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WHY involve the patient in research?

  • It is patients (service users) who identify the issues which are important to them and help researchers identify the important research questions (Hanley, 2000). 

  • Patients often provide different views which result in innovative and imaginative solutions unthought of by healthcare professionals (DoH, 1999b). 

  • The systematic review by Crawford et al of involving patients in the planning and development of services confirms that service users do contribute to changes in service provision (Crawford, 2002).

My current research into the fears and concerns of patients about stopping antidepressant medication is a research question identified by patients in the earlier research I undertook as part of an MSc.

 

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WHY worry about patients' fears and concerns?

  • The clinical problem for the healthcare professional is to know how to respond to patient fears about stopping antidepressant medication in order to avoid long-term use of expensive medications in patients who may no longer need them. 

  • A knowledge of this fear, an understanding of what it is the patient dreads, and an understanding of what model of recovery the patient has, if indeed they actually have a model of recovery, will facilitate the development of an appropriate counselling strategy(s) for use by healthcare professionals in primary care. 

  • These are important aspects in depression which require their own evidence base.

 

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Disclaimer

This website is intended to provide helpful and informative material on the subject of depression.
It is not intended to provide medical advice to patients.
All information in this website is the sole responsibility of Penny Louch.
 

Last updated 17 August 2008

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Copyright ©2006 Penny Louch